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font-family: "Helvetica Neue", Helvetica, Arial, sans-serif; letter-spacing: 1px; background-color: rgb(255, 255, 255);">在疫苗、血制品、生物制品、药品、保健品等方面使用要求也越来越高。</span><span style="color: rgb(51, 51, 51); font-family: "Helvetica Neue", Helvetica, Arial, sans-serif; letter-spacing: 1px; background-color: rgb(255, 255, 255);">制药冷冻干燥机与冻干物质直接或间接接触的部件有干燥箱及捕水器，干燥箱与捕水器内含有各种机械零件都有可能成为藏污纳垢的场所，为了提高冻干制品的质量，干燥箱及捕水器必须进行灭菌消毒。</span><br style="box-sizing: border-box; color: rgb(51, 51, 51); font-family: "Helvetica Neue", Helvetica, Arial, sans-serif; letter-spacing: 1px; white-space: normal; background-color: rgb(255, 255, 255);"/><span style="color: rgb(51, 51, 51); font-family: "Helvetica Neue", Helvetica, Arial, sans-serif; letter-spacing: 1px; background-color: rgb(255, 255, 255);"> 利用高温、高压对设备进行灭菌消毒是一种最有效、最彻底方法，但<a href="http://www.tfyqchina.cn/" target="_self">冷冻干燥机</a>是一种低温、低压设备，因此对于干燥箱及捕水器的制造提出了更高的要求，尤其是干燥箱为矩形压力容器，干燥箱门要经常开启，因此蒸汽灭菌时干燥箱的锁紧装置既要承受高温、高压(正压)，又要承受低温、低压(负压)。</span><br style="box-sizing: border-box; color: rgb(51, 51, 51); font-family: "Helvetica Neue", Helvetica, Arial, sans-serif; letter-spacing: 1px; white-space: normal; background-color: rgb(255, 255, 255);"/><span style="color: rgb(51, 51, 51); font-family: "Helvetica Neue", Helvetica, Arial, sans-serif; letter-spacing: 1px; background-color: rgb(255, 255, 255);"> 早期的蒸汽灭菌<a href="http://www.tfyqchina.cn/" target="_self">冷冻干燥机</a>的锁紧装置采用压力容器传统的螺栓锁紧方法，就是在干燥箱的箱门周围安装若干螺栓进行锁紧。这种方法虽然可靠性较好，制造比较方便，但是操作人员的劳动强度教高，而且螺栓结构容易藏污垢，不符合GMP生产的要求。</span></p><p><span style="color: rgb(51, 51, 51); font-family: "Helvetica Neue", Helvetica, Arial, sans-serif; letter-spacing: 1px; background-color: rgb(255, 255, 255);"><br/></span></p><p><span style="color: rgb(51, 51, 51); font-family: "Helvetica Neue", Helvetica, Arial, sans-serif; letter-spacing: 1px; background-color: rgb(255, 255, 255);"><span style="box-sizing: border-box; margin: 0px; padding: 0px; border: 0px; outline: 0px; font-size: 14px; vertical-align: baseline; list-style: none; color: rgb(51, 51, 51); 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